clar697
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A 22-year-old man with HIV infection has an eye infection due to herpes simplex virus 1 (HSV-1) that is resistant to acyclovir. Development of acyclovir resistance is most likely due to a mutation of which of the following genes of HSV-1?
A) Glycoprotein C
B) Major capsid protein
C) Ribonucleotide reductase
D) Thymidine kinase
E) Uracil DNA glycosylase
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| jaweriah
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D
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| vaibhavbora
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d
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| brainstem
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D - it shud be activated by triphosphorylation : 1 by viral kinase, 2 by host kinase.
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