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clar697
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07/04/08 - 09:23 AM             #1

A 52-year-old man with alcoholism comes to the physician for a follow-up examination. He has hypertension, type 2 diabetes mellitus, osteoarthritis, and dyslipidemia. Current medications include metformin, glyburide, metoprolol, and sildenafil. Three months ago, he began to follow a diet recommended by the American Heart Association because of an increased serum LDL-cholesterol concentration. He has been adherent with this new regimen. His blood pressure is 135/85mmHg. Physical examination shows spider angiomata on the face. Fasting studies show a serum LDL-cholesterol concentration of 148mg/dL. The physician is considering prescribing pravastatin. This drug should be used with caution because of adverse effects associated with which of the following conditions?

A) Alcoholism
B) Erectile dysfunction
C) Hypertension
D) Osteoarthritis
E) Type 2 diabetes mellitus


SpeaksSoftly
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07/10/08 - 01:32 PM             #2

I am guessing A because statins are pretty rough on the liver. So if a person is alcoholic I would think this increases the possible damage to the liver.


supra
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07/12/08 - 08:32 AM             #3

A.Pravastatin is USED with caution in alcoholics coz of fera of hepatic damage.


DRFP
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10/27/08 - 01:51 PM             #4

supra wrote:
A.Pravastatin is USED with caution in alcoholics coz of fera of hepatic damage.

Yes statins/Alcohol/ liver bad combos

A

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brainstem
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10/27/08 - 08:45 PM             #5

A - as statins r hepatotoxic, shud be used with caution in liver dis pts, alcoholics.

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vaibhavbora
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11/26/08 - 12:10 AM             #6

a , spider angiomata , show liver function compromised


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