clar697
Forum Guru
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A 35-year-old man who is planning to go on Safari in East Africa for 4 weeks comes to the physician for prophylaxis against malaria. Which of the following drugs is most appropriate?
A) Diethylcarbamazine
B) Ivermectin
C) Mefloquine
D) Praziquantel
E) Trimethoprim-sulfamethoxazole
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| clar697
Forum Guru
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I chose C – Mefloquine. It is an anti-malarian drug used for suppressive prophylaxis. Mefloquine is only effective at killing the malaria parasite once it has entered the erythrocytic stage (blood stage) of its life cycle, and therefore has no effect until the liver stage is complete. Therefore, the patient must continue to take the prophylactic drug for four weeks after leaving the area of risk. Side effects are severe depression, anxiety, paranoia, aggression, nightmares, insomnia, seizures, peripheral motor-sensory neuropathy, vestibular damage, central nervous system problems, and suicidal ideation.
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| atulkalanuria
Forum Newbie
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yeah i think C shld be the answer.
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| alirizvi
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We are what we repeatedly do. Excellence, therefore, is not an act, but a habit. - Aristotle.
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| a3112
Forum Senior
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C
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| vaibhavbora
Forum Elite
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c , africa , endemic and also high incidence of chloroquine resstence
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VB
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| brainstem
Forum Guru
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C
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