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Kaplan Qbank USMLE



Author5 Posts
  #1

Which of the following modifications of an endogenous pharmacologically active peptide would be most likely to slow the metabolism of the peptide, thus decreasing its clearance and increasing its half-life?

A
) Administering the peptide with an enteric coating

B
) Decreasing the number of amino acids in the peptide

C
) Ensuring a free amino group at the N terminal

D
) Ensuring a free carboxyl group at the C terminal

E
) Substituting a D for an L amino acid

  #2

ONLY CHOICE MAKE SENSE IS =E

  #3

Iam also thinking in terms of E as the best choice.

Don't have answer for this Q

  #4

can u explain me how?
plsssssssssssssss :roll:

  #5

i believe is E also.

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