Prep for USMLEPrep for USMLE Forum
   Forum    Step 1  Step 2 CK Step 2 CS Step 3  Match  IMGs Resources Search






Previous Topic | Next Topic  Q - RENAL 




 



Author4 Posts
  #1

the effect of aldosterone on the principal cells of the distal convoluted tubule is to:
a) increase the synthesis of sodium pumps
b) increase the cells permeability ot water
c) increase retention of potassium ions
d) increase the cells' secretion of antidiuretic hormone
e) trigger the release of renin

need feedback ......explain the answer pls....thank you

___________________
truth is great yet truthful living is the greatest....smiling face
Mili

  #2

Aldosterone increases the reabsorption of sodium by increasing the number of apical Na+ channels and increasing the synthesis of Na+/K+ ATPases in the basolateral membrane of the distal convoluted tubule cells. A greater amount of Na+ is reabsorbed through these channels, and to maintain the intracellular concentration of sodium, more Na+ is pumped out (and more K+ is hence excreted).

So (a).

  #3

yes

water permeability is mediated by ADH, so (b) is wrong
aldosterone stimulates K+ secretion, so (c) is wrong
ADH secretion, by the posterior pituitary, is regulated by serum osmolarity, so (d) is wrong
renin is secreted by the JG cells, in response to either low effective blood volume or by high concentration of filtered urine. as reported by the macula densa, so (e) is wrong.

hope this helps.

  #4

thank you guys smiling face ...

___________________
truth is great yet truthful living is the greatest....smiling face
Mili







You don't have permission to post.




Login or Register to post messages in this topic





















Contact | Leaders | Disclaimer | Privacy

Copyright @ Prep for USMLE. All rights reserved.