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Kaplan Qbank USMLE



Author7 Posts
  #1

Which of the following is most likely to cause an increase in filtration fraction?

A) Decreased glomerular filtration coefficient
B) Increased afferent arteriolar resistance
C) Increased efferent arteriolar resistance
D) Increased plasma protein concentration
E) Increased renal blood flow


  #2

C

  #3

C

  #4

C

  #5

EASY C nodnodnod

___________________
FUTURE 99ER

  #6

its B
because by increasing afferent arteriolar resistance we decrease blood flow & FF= GFR/RBF.

  #7

no thats not right. ok look... if you increase the resistance at the afferent arteriole, you will decrease blood flow, and you will decrease hydrostatic pressure within the glom cappilary which decreases GFR, therefore you are wrong. in order for filtration fraction to increase with the fraction GFR/RBF...anything that constricts the AFFERENT arteriole...it will decrease GFR. since we are speaking about increasing filtraation fraction the right answer is C. by constricting the efferent arteriole, we are mimiking the effects of renin-angiotensin 2 effects, whose primary role is to increase the hydrostatic pressure in the glom cappillary, however that is a short term effect, by constricting the efferent, you also decrease blood flow to the peritubular cappilaries which reduces blood flow, which still would increase the FF.... : )







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