NBME F5 S2 facial hair in menopause

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NBME F5 S2 facial hair in menopause

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7 Posts

clar697
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06/30/08 - 07:15 AM

A 55-year-old woman comes to the physician because of increased facial hair growth over the last 8 years. Menopause occurred at age 45. Laboratory studies of the serum show:

Testosterone 80 ng/dL (N=20-90 ng/dL
Dehydroepiandrosterone sulfate 320 ug/dL (N=60-350 ug/dL)
Thyroid-stimulating hormone 0.8 uU/mL
Estradiol 20 pg/mL
Progesterone decreased

Which of the following is the most likely cause of the increased facial hair growth?

A) Decreased 5-alpha reductase activity
B) Decreased adrenal androgen production
C) Decreased androstenedione peripheral conversion
D) Decreased inhibin production
E) Increased ovarian androgen production
F) Increased testosterone:estrogen ratio

Is it F?

usmlekiller
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Topics: 11
Posts: 609

06/30/08 - 03:52 PM

i think C

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tdbchoco
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07/02/08 - 10:24 AM

Isn't it F?

gladiator9
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07/02/08 - 10:46 AM

I think its C

tiz_83
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07/15/08 - 12:50 AM

I think its C.
After menopause primary source of estrogen is estrone which is formed by peripheral conversion of androstenedione to estrone.

LG
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07/24/08 - 05:21 PM

I think is F too clar697

littledoc
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07/26/08 - 05:23 PM

i think its C. In women androgens are responsible for body hair & during menopause ovaries atrophy & will not convert androgens to estadiol, leading to elevated androgen & body hair

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