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Kaplan Qbank USMLE



Author5 Posts
  #1

Several children who are members of a family with a hereditary deficiency of C6 have Neisseria meningitidis-induced sepsis. Incubation of antibody-coated N. meningitidis with plasma from the affected children is most likely to produce which of the following findings?

A) Decreased bacterial killing and decreased generation of anaphylatoxins
B) Decreased bacterial killing and normal generation of anaphylatoxins
C) Normal bacterial killing and decreased generation of anaphylatoxins
D) Normal bacterial killing and normal generation of anaphylatoxins





  #2

b?


  #3

b

Defect is starting from C6, so C5a, C3a and C4a (anaphylatoxins) are still being made, but after C6 the MAC (Membrane attack complex) doesn't work.

At least that's what I think.

  #4

B


  #5

jorgefhoyos wrote:
b

Defect is starting from C6, so C5a, C3a and C4a (anaphylatoxins) are still being made, but after C6 the MAC (Membrane attack complex) doesn't work.

At least that's what I think.



well said. I would have said the same, but you saved me time typing.







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