cirus
Forum Guru
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In kaplan it states that Hyperventilation or supplemental O2 increases PaO2, but has little effect on Total O2 Content, can someone plz explain
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| Jackofknives
Ipwnpoker.com
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O2 is carried in blood in 2 forms, bound to hemoglobin in RBC and physically dissolved.
Vast majority of O2 content in the blood is carried by hemoglobin. Since hemoglobin is 100% saturated at 100mm Hg O2 tension, increasing POI tension will not increase the O2 binding capacity of hemoglobin any further.
PaO2 is referring to the amount of O2 physically dissolved in plasma. The higher the POI tension the higher amount of O2 will be dissolved in plasma. However, its contribution of total O2 content is insignificant.
In conclusion. increasing PIO2 will increase the physically dissolved O2 in plasma, but will not increase the total O2 content in the blood as the whole.
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| cirus
Forum Guru
Topics: 108
Posts: 740
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thanx, appreciate it
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