spinal shock Forum Senior

Topics: 13 Posts: 186
| | 06/03/08 - 02:27 PM  
 
   
 
|   #1 |
abnormalities in the cytosolic copper-zinc superoxide dismutase (sod1) gene on chromosome 21 have been i dentified as factors in the pathophysiology of which degenerative disorder a.parkisons diease b.amyotrophic lateral sclerosis c.huntingtons chorea d.alzhiemers diease e.tuberous sclerosis explain plz
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| jean robert Forum Guru

Topics: 164 Posts: 676
| | 06/03/08 - 03:27 PM  
 
   
 
|   #2 |
b.-ALS
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| study499 live@ur full potential

Topics: 5 Posts: 589
| | 06/03/08 - 05:16 PM  
 
   
 
|   #3 |
yes, ALS... & for explanation: most cases of ALS are sporadic, however when it is a case of familial, there is a defective superoxide dismutase gene on chrom 21.....so there wld be a superoxid free radical damage to neurons....
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| Tiff Forum Guru
Topics: 55 Posts: 581
| | 06/03/08 - 09:14 PM  
 
   
 
|   #4 |
B
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| spinal shock Forum Senior

Topics: 13 Posts: 186
| | 06/04/08 - 07:20 AM  
 
   
 
|   #5 |
 
___________________ we expect others wishes, we dont miss something that we dont expect to have
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| supra Forum Elite

Topics: 19 Posts: 353
| | 06/04/08 - 09:09 AM  
 
   
 
|   #6 |
THANKS 4 THE GOOD QUESTION SPINAL SHOCK,I LEARNT A new point 2day.
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| pioneer Forum Newbie
Topics: 0 Posts: 5
| | 06/05/08 - 01:52 AM  
 
   
 
|   #7 |
that was good question SPINAL SHOCK ,therefore more comment: cytosolic copper-zinc superoxide dismutase (SOD1) mutations cause type 1 amyotrophic lateral sclerosis.this abnormality in the enzyme is replaces the amino acid alanine with the amino acid valine at position 4 in the enzym, that is the etiology of continued stimulation of motor neurons in specified locations that causes them to burn out and die (excitotoxicity). and genetic etiology of the disorder in molecular Location on chromosome 21 is at base pairs 31,953,805 to 31,963,114
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| medikus Forum Senior
Topics: 49 Posts: 97
| | 06/05/08 - 01:02 PM  
 
   
 
|   #8 |
B
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