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Author7 Posts
  #1

A 27 yr old woman has suprasellar craniopharyngeoma which leads to pressue induced atrophy of posterior pituitary. Which of the following responses is most likely in the kidney?
a) decreased production 1,25 dihydrocholecalciferol
b) decreased sodium reabsorption in PCT
c) increased calcium reabsorption in proximal tubule
d) increased water reabsorption by thick limb of loop of Henle
e) production of hypotonic urine

Any help is apreciated. Thanks!

  #2

E


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  #3

E decrease vasopresin production leading to increasing water secretion with subsequent urine dilution

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  #4

I will go with E

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  #5

yeah i would go for E, it's the only logical answer but just 1 question:
Vasopressin and oxytocin are produced in hypothalamic nuclei and then transported via the pituitary stalk to the posterior pituitary where they are released... (that's why in transection of the pituitary stalk, after an initial acute phase of decrease release of post pit. hormones, they return to normal and are secreted from the hypothalamus)
any thoughts???????????? why would there be decrease hormones release

  #6

v answered here E as initial effect of dec ADH, after that urine osmolarity come back to normal i too agree that but Q is not specific about initial r late effect & fortunately options r clear does not have both,so no confusion.v can pick e with 100% confidense.



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  #7

y shud ADH dec initially even though it secreted frm hypothalamus. i dont have ans 4 that.
anybody expl helpful.

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