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Kaplan Qbank USMLE



Author6 Posts
  #1

Young man, have DM-I ,tell the doctor that he like drink beer alot with his friends.
He is playing sports , but sometimes he complain from symptoms of decreased blood sugar. What s the roe oh alcohol ??

1. compete with glucose for absorption in gut

2.inhibit glucose synthesis


  #2

I think that alcohol inhibit glucose synthesis, since metabolism of alcohol produce a lot of energy and there is no need for glycose to be degraded. That is my thinking . I might be wrong?

  #3

no need for glucose to be synthesized, nod degrades, sorry

  #4

the biochemical mechanism for alcoholic hypoglycemia is that the increased NADH/NAD will decrease the rate of gluconeogenesis, because that increased ration diverts the metabolites that are used for gluconeogenesis away from that pathway, e.g: increased formation of glycerol from DHAP, and increased formation of lactate from pyruvate ,if we consider the AA coming through the cori cycle will yeild a pyruvate molecule, which is the pathway that AA go through during gluconeogenesis..

  #5

gingerbread got whole idea /thats all.


  #6

gingerbread wrote:
the biochemical mechanism for alcoholic hypoglycemia is that the increased NADH/NAD will decrease the rate of gluconeogenesis, because that increased ration diverts the metabolites that are used for gluconeogenesis away from that pathway, e.g: increased formation of glycerol from DHAP, and increased formation of lactate from pyruvate ,if we consider the AA coming through the cori cycle will yeild a pyruvate molecule, which is the pathway that AA go through during gluconeogenesis..


perfect answer

we should know this by heart


also how does alcohol get to increase lipids and cause fatty liver







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