jean robert
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A 50 yr old woman with swan-neck deformity of the hands and enlarged knuckles develops large subcutaneous nodules near her elbows.If the nodules were biopsied, which of the following best describes their likely histological appearance?
a) Amorphous crystalline mass surrounded by macrophages
b) Cystic space caused by myxoid degeneration of connective tissue
c) Darkly pigmented synovium with an exuberant, villous growth
d) Fibrinoid necrosis surrounded by palisading epithelioid cells
e) Well- encapsulated nodule of polygonal cells within a tendon sheath
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| new_n_lost
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d) Fibrinoid necrosis surrounded by palisading epithelioid cells
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| jean robert
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Correct Ans D
EXPLANATION
Swan-neck deformity,enlarged knuckles, and subcutaneous nodules are classic clues for RA. The subcutaneous rheumatoid nodules are composed histologically of areas of fibrinoid necrosis surrounded by palisading epithelioid cells
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