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Author8 Posts
  #1

A 39-year-old African-American woman is brought to the health center at 7:00 PM by her children because of weakness and numbness in her right leg. She also says, "I have an odd feeling in my left leg." The symptoms started several days ago and gradually have increased. She also experienced low back pain about 10 days ago, which responded until recently to oral morphine and ibuprofen prescribed by her primary care physician, whom she could not reach tonight. She has had no problems with bowel or bladder function. She was treated 4 months ago with mastectomy, chemotherapy and radiation therapy for infiltrating ductal carcinoma of the left breast. Neurologic examination today discloses weakness of all muscle groups in the right leg and thigh, with normal strength in the left leg. There is marked decrease in sensation to pinprick and temperature up to the area of the inguinal ligament on the right, and decreased perception of position and vibration sense in the left lower extremity. The patellar and Achilles reflexes are hyperactive on the right and those on the left are normal. Rectal sphincter tone is normal. Diagnostic studies show metastatic disease to L2 with minimum invasion of the spinal canal. Which of the following is the most appropriate method to control her pain?

A) Chemotherapy
B) Dorsal rhizotomy
C) Long-acting oral morphine therapy
D) Radiation therapy
E) Surgical decompression

  #2

D

  #3

I agree. No given answer.

  #4

It si D

  #5

why not E?

  #6

Tuscani wrote:
why not E?


Cause D is much easier, has less side effects etc... Don't cut someone open unless you really have to.

Edited by romano on 08/24/08 - 08:00 AM

  #7

It is D , for cord compression syndrome after MRI and high dose dexa administration , if the etiology is metastatic cancer go for Radiotherapy and if it is due to hematoma go for surgical decompression.


  #8

nightflight1945 wrote:
It is D , for cord compression syndrome after MRI and high dose dexa administration , if the etiology is metastatic cancer go for Radiotherapy and if it is due to hematoma go for surgical decompression.


No doubt if there is no S/S of cord compression radiotherapy (provided primary tumor is radiosensitive) is the therapy of choice .But ,if cord compression is there then surgical intervention takes priority :



Metastatic vertebral tumors not associated with pathologic fracture causing cord compression by bone fragments may be treated with x-ray therapy, which is to be administered on an emergency basis in the presence of epidural intraspinal tumor mass if there is beginning loss of function and a pathologic diagnosis has previously been made. The indications for operation to treat metastatic spine tumors are as follows: (1) rapid progressive loss of function; (2) presence of a known radioresistant tumor; (3) undiagnosed mass, especially with the possibility of another diagnosis, such as abscess or hematoma; (4) recurrence or progression of symptomatic tumor growth after radiation therapy; and (5) presence of progression of symptomatic spinal deformity due to vertebral instability. Radiation therapy may be used in conjunction with operative decompression and stabilization to retard or prevent recurrence. Radiation therapy alone should be used to relieve pain when spinal cord function is intact and there is no evidence of bony compression

Ref: Current surgical diagnosis and treatment

The patient has
  1. Just 10 days history of spinal cord symptoms (rapid progression)
  2. S/S of cord compression are there










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