New Q

Prep for USMLE Forum

» Log in | Register

Forum

Step 1

Match

Prep4USMLE Forum » USMLE Step 1 Forum » Pathology Forum

New Q

Author

10 Posts

jean robert
Forum Guru
avatar

Topics: 164
Posts: 676

05/13/08 - 11:46 PM

At autopsy, a patient who had died with acute anuria and uremia is found to have ischemic necrosis of the cortex of both kidneys with relative sparing of the medulla.These pathological findings are most likely to related to which of the following underlying conditions?

a) DIC

b) Multiple myeloma

c) Polycystic Kidney Disease

d) Pyelonephritis

e) Sickle anemia.

___________________
Great works are performed not by strength, but by perseverance.

1.ammara
Forum Junior
avatar

Topics: 8
Posts: 85

05/14/08 - 12:27 AM

A. DIC

___________________
Plan ahead, it wasn't raining when Noah built the Ark!

Tiff
Forum Guru

Topics: 55
Posts: 581

05/14/08 - 05:20 AM

D - pyelonephritis

Aashi
Forum Moderator
avatar

Topics: 113
Posts: 1,061

05/14/08 - 07:31 AM

Cortical necrosis of cortex sparing the medulla---------------->Key feature in DIC----------->A

___________________
"Obstacles are those frightful things you see when you take your EYES off your goal."

Tiff
Forum Guru

Topics: 55
Posts: 581

05/14/08 - 08:13 AM

Still have much to learn. rolling eyes

My resources don't explain this key feature of DIC. Where would I find such info?

Tiff
Forum Guru

Topics: 55
Posts: 581

05/14/08 - 08:40 AM

I simply can't see the relationship between DIC and anuria. Anuria is usually caused by stones. Stones can be a complication of pyelonephritis. After looking up this topic, I'm left even more confused. Isn't this a case of renal paillary necrosis? and is not pyelonephritis a cause? What am I missing? raised eyebrow

Tiff
Forum Guru

Topics: 55
Posts: 581

05/14/08 - 09:20 PM

Anyone with any thoughts to explain??

jean robert
Forum Guru
avatar

Topics: 164
Posts: 676

05/14/08 - 11:12 PM

DIC------> Heavy Bleeding ----------->dramatic drop in blood pressure---------> decrease renal perfusion-----------> Anuria

___________________
Great works are performed not by strength, but by perseverance.

Tiff
Forum Guru

Topics: 55
Posts: 581

05/15/08 - 10:33 AM

If anyone knows where i can find more information about this please let me know. After doing some more reading, I finally get it. Pyelonephritis as sequelae of renal papillary necrosis can't be correct because the medulla is not spared. I know it's probably not a suprise to many of you, but I'm relieved now because a little light bulb just went on in my head. grin

new_n_lost
Forum Hero
avatar

Topics: 722
Posts: 6,313

05/15/08 - 02:02 PM

#10

Tiff wrote:
, but I'm relieved now because a little light bulb just went on in my head. grin

Happens to me all the time esp when i m not studying but mulling over things in my mind and i go "Ahan thats why " grin

___________________
"never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

You don't have permission to post.