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Kaplan Qbank USMLE



Author4 Posts
  #1

46. An 80-year-old woman comes to the physician because of a 10-year history of slowly worsening pain in both knees. She has a 20-year history of hypertension and worked as a housekeeper most of her adult life. Physical examination shows irregular bony prominences around the tibial plateau at the knee joint line bilaterally and moderate bilateral knee joint effusions. X-rays of the knees show thinned cartilage and extensive osteophyte formation. Which of the following is the earliest stage in the development of this condition?

A Cracking of the cartilaginous surface
B Marginal osteophyte proliferation
C Neovascularization
D Seepage of articular fluid into the bone
E Subchondral bone cyst formation


  #2

Looks like she has bone spurs - Choice B


  #3

Changing my answer to A. Didn't properly read the question which is really asking for the earliest stage of osteoarthritis. That would make A reasonable. Cracking of the cartilage would have to occur 1st before the growht of spurs many years later.


  #4

yes .. A ...nod

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