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Author5 Posts
  #1

What is Coombs serum?

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Smell the coffee! "Is That an Osler move??"

  #2

NEVER HEARD OF THIS. COULD U PLEASE REPHRASE YOUR QS.

  #3

its anti human gamma globulin used in the Coombs test

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Smell the coffee! "Is That an Osler move??"

  #4

Coombs serum is used in Blood Banking. I haven't done BB since 1988. Here's a link to information about a Direct Coombs test:

http://www.nlm.nih.gov/medlineplus/ency/article/0...

Indirect Coombs testing is the same as the "screen" part of a "type and screen" order for BB. Here's a link:

http://www.nlm.nih.gov/medlineplus/ency/article/0...

http://www.gpnotebook.co.uk/cache/1771700246.htm

Here's another link.

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Clinical Microbiology since 1974

  #5

Coombs serum is "anti-human gamma globulin".
They make it by immunizing a horse or another animal with human gamma globulin.
Then the horse makes anti-human gamma globulin.

This coombs serum put in a human and can be used to detect autoantibodies against human RBC's in Hemolytic Anemia.
(the anti-human gamma globulin will bind the autoantibodies on the patient's RBCs) This can be seen by clumping of the blood.


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