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8 mo old baby with progressive conjugated jaundice, serology negative for hepatitis, whats the best test to dx biliary atresia?
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| prep4usmle
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If BB is < 10mg there is a good chance to diagnose biliary artesia with HIDA scan after 5 days of phenobarbital.
The test should reveal a normal uptake by hepatocytes but failure of isotope excretion in intestin after 24 hours.
Liver biopsy to confirm the diagnostic.
US to exclude a stone/cyst
Blueprint page 202
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| no more a loser
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| | 06/27/03 - 04:37 AM
1 of 1 forum leaders found this post helpful
| #3 |
CORRECT 
yes HIDA scan after a week of phenobarbitol
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| doublebubble
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Ultrasound
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| usmlebuzz
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why after 5 days of phenobarbital. ? :icon_scratch:
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| alice8
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:arrow:
Phenobarbital Role:
phenobarbital stimulates the activity of glucuroyl transferase and the synthesis of Y and Z carrier proteins and therefore increases uptake and conjugation of bilirubin
a 3-7 days course of phenobarbital therapy increases the sensitivity of HIDA scan in differentiating between biliary atresia and other causes of neonatal cholestasis
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| usmlebuzz
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thanks Alise :lol:
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| alice8
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not at all riSu :lol:
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| LC
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Does a person have to hold still for a long time during a HIDA scan? Is a HIDA scan as good as an MRI? Why did my gastroenterologist not mention a HIDA scan to determine if there is a gallstone blocking my bile duct? He only mentioned an MRI.
LC
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| no more a loser
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well hospitals have different management techniques. these answers r based on usmle preference, that doesnt necessarily mean actual hospitals do these things in reality. another thing i am sure u r not 8 mo old, i mean this is for pediatric population
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