new_n_lost wrote:
wht i was trying to say abt Multifactorial Inheritance is that Multiple Factors Cause the Same Result.
Not necessarily!
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| new_n_lost
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Ok then Explain How Wud Different Factors wud Lead to Different Tumors
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| mytime
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Bhaai if the genes afftected is a tumor suppressor like p53 which can cause N no of tumors. Then there is MULTIfactorial causes of tumors. What we have to get is that they are talking of is Li Fraumeni's.
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| mytime
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Besides that the only othe MOST likely answer wud be Variable expressivity. Even though everything is correct to some extent.
Point is u have to understand that still sreasearch is underway so pick what u are comfortable with and MOVE ON! 
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| new_n_lost
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BHen u r imply that Multifactorial Inheritance is Leading Cause of the Pattern of inheritance in the scenario provided. but the point is that Multifactorial Inheritence Cant be the same in the all the generations thus implying this syndrome as familial hence the only thing left is that Either u Chose Variable Expressivity or Anticipation. Variable Expressivity doesnt make sense cos they r getting the Cancers but at a much younger age.
Khair Like U Said U want to Move On. SO LEts 
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| mytime
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Btw u misunderstood the bhai!!!!! It was an exclamation!!!!!!
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| new_n_lost
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Arey Hum Lucknow Walay Hain Isi tarah KEhtay HAin 
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| mytime
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| dr ruman
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yeah,
its multifactorial inheritance ,which explains so many different disease in same family.fo all other explanation the characteristics are realted to only one disease pattern.
eg,variable expression means variability in severity of same disease
anticipation,again same disease but early onset of symptoms with increasing severity
genotypic heterogenecity ,same disease but different expression of severity between different families,not in same pedigree
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