Dr_C
Forum Newbie
Topics: 3
Posts: 26
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can somebody help me out, i'm a little confuse about giving Oxygen to a copd patient, I've been reading that giving oxygen to a severe copd patient may increase it's PCo2 because by increasing PaO2 we decrease alveolar ventilation ( that is by increasing dead space)and since alveolar ventilation is a factor affecting PACO2, hypoventilation would increase PCO2.
What should be the proper way to administrate O2 to a copd patient? because at end oxygenotherapy is required for copd patients. 
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| sigh
Forum Senior
Topics: 15
Posts: 152
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If you give a pt with COPD O2 at for ex. 2L/min it will be OK. Just don't go too high...
"The ventilatory drive of patients with chronic lung disease is primary due to their hypoxemia, rather than CO2 levels...Administartion of a high O2 mixture to relieve the hypoxemia is contraindicated because this removes the hypoxic drive, leading to severe hypoventilation"- Kaplan.
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| 1.ammara
Forum Junior
Topics: 7
Posts: 56
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Yes, that is why COPD patients are given low con. oxygen therapy, like 60% or so. not 100%
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| Dr_C
Forum Newbie
Topics: 3
Posts: 26
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thanks guys, i've been reading a lot bout it and finally got the same answer, i really do appreciate ur comments. Once again thanks!
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| Dr_C
Forum Newbie
Topics: 3
Posts: 26
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it's all about the chemoreceptors in a COPD patient with CO2 retention, as we know these CO2 receptors can adpat and if there is a chronic retention of CO2 these CO2 receptors will stop functioning, but the O2 receptors will keep working at a low level because they will never adapt, therefore if we administrate 100% O2 these O2 receptors will stop functioning so the only drive for ventilation will be lost as "Sigh" mentioned and this will create a severe intracelular acidosis.
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