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Kaplan Qbank USMLE



Author7 Posts
  #1

A gene encodes a protein with 150 amino acids. There is one intron of 1000 bps, a 5' untranslated region of 100 bp, and a 3' untranslated region of 200 bp. In the final processed mRNA, how many bases lie between the start AUG codon and the final termination codon?

A. 1750
B. 750
C. 650
D. 450
E. 150

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  #2

3 x 150 = 450

  #3

That is correct asmi, could you please explain this, man i am really bad at biochem???

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"If He takes you to it, He'll take you through it."

  #4

oh nevermind, sorry, i get it.

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"If He takes you to it, He'll take you through it."

  #5

No problem

  #6

can u plsssssssssss explain how????

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  #7

see. he says that the ultimate protein has 150 aminoacids. so it shud be coded by a gene with atleast 450 basepairs in the EXON(the part which gets expressed)now he has given a distractor saying there are X and Y basepairs in INTRON . if he has asked how many base pairs in the unprocessed product RNA i would include all 450 and whatever numbers he has given. but now he is asking processed RNA (which he means it has undergone SPLICING) SO THAT MEANS only the expressible base pairs are left. so there are only 450.

thats the answer


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