hottie99
Forum Guru
Topics: 32
Posts: 666
|
hi, can somone please explain this one?
___________________
83/86/pass/2 us lors/2005 grad/citizen
|
| taipei817
Forum Junior
Topics: 2
Posts: 81
|
tough one, my guess is vancomycin, as it is only restricted in the GI tract and can be used to treat C diff, a 'potentially' serious systemic infection. i cannot predict eh bioavailability of other drugs at all!
|
| hottie99
Forum Guru
Topics: 32
Posts: 666
|
i wanted to pick vanco too, i thought it was only oral out of those.. they have B as the answer, which is cipro, i didnt get why, hmm....
___________________
83/86/pass/2 us lors/2005 grad/citizen
|
| Tiff
Forum Guru
Topics: 54
Posts: 561
|
I think the key words to this question is oral bioavailibility. All the others have very limited if not poor oral bioavailibility for systemic infections making cipro a great choice.
|
| hottie99
Forum Guru
Topics: 32
Posts: 666
|
but wat do u mean by bioavailablity then? im confused... thx tiff!
___________________
83/86/pass/2 us lors/2005 grad/citizen
|
| lakshya_0_7
Forum Elite
Topics: 27
Posts: 359
|
vanco if given orally would be great to kill the bacterias in the colon ONLY it doesnt get absorbed at all!!!.....thats why it would kill clostridium difficile.....it wont get absorbed at all......here we need a drug for systemic infection so we cant choose vancomycin.....cipro is the ans
___________________
99/99/pass,1 uslor, research(1mo), 2008 grad,need visa, applied on 5 sept,131-IM only,I/R-3/1!!
|
| 1.ammara
Forum Junior
Topics: 8
Posts: 72
|
None of the drugs except Ciprofloxacin has good oral bioavailabilty, i mean they are absolutely not absorbed from the GI. if we have to use these drugs, we must adminiter them parenterally. since we have to treat a potentially serious "systemic" illness, that means "orally" given drug must be absorbed from GI and act systemically. Cipro is the only drug thats absorbed form GI among these. Simple!
___________________
Plan ahead, it wasn't raining when Noah built the Ark!
|
| drshvetasm
Forum Elite
Topics: 22
Posts: 285
|
B is the only drug out of the rest which is given orally...the only available route for vancomycin,gentamicin,amphotericin and polymixin is iv...so only one with predictable oral bioavailabilty wud be cipro.
|
| Tiff
Forum Guru
Topics: 54
Posts: 561
|
hottie99 wrote:
but wat do u mean by bioavailablity then? im confused... thx tiff!
Bioavailability is the rate that the drug enters the systemic system.
|
| spinal shock
Forum Senior
Topics: 13
Posts: 182
|
B bio availability is the amount of drug reaching the circulation in unchanged form
___________________
we expect others wishes, we dont miss something that we dont expect to have
|
| Tiff
Forum Guru
Topics: 54
Posts: 561
|
spinal shock wrote:
B bio availability is the amount of drug reaching the circulation in unchanged form
More like the rate of how much drug is available in circulation.
|
| hottie99
Forum Guru
Topics: 32
Posts: 666
|
thx so much, got itnow!! i gues i didnt know some of those other rx were oral or just iv, but i appreciate!!
___________________
83/86/pass/2 us lors/2005 grad/citizen
|
|
| |
| | | | | | | | | | | | |
