drug induced lupus & nephritis?

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drug induced lupus & nephritis?

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9 Posts

peter90036
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Topics: 28
Posts: 315

04/21/08 - 12:06 PM

i dont remember

does drug induced lupus have renal involvement?

peter90036
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04/21/08 - 12:28 PM

the answer to that is NO

mildus
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04/21/08 - 12:45 PM

it doesn't have CNS involvment

liliaeliz
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Topics: 38
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04/21/08 - 01:41 PM

hidralazine procainamide INH ALFAMETIL DOPA CLORPROMACINE .SEROSITIS ,ARTHRALGIAS ,FEVER NO RENAL OR CNS INVOLVEMENT ,ANTIHISTONE POSITIVE

Eagle_303
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Topics: 18
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04/21/08 - 02:11 PM

Thread Extension :

Another characteristic is common among Hydralazine ,INH and Procainamide ,in addition to be responsible for DIL .What is that characterisitic ?

Janka
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Topics: 28
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04/21/08 - 02:25 PM

drug induced hemolytic anemia? ass/w G6PD at least for INH and hydralazine, not sure about procainamide but that one definitely also plays a role.

peter90036
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04/21/08 - 04:22 PM

dunno... make us wiser Eagle smiling face

Eagle_303
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04/21/08 - 04:49 PM

Hydralazine ,Procainamide and INH ,all three of them are metabolized by acetylation.

So in slow acetylaters their blood concentration is comparatively high while in rapid acetylators they have low blood concentrations at equal doses .

peter90036
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04/21/08 - 05:02 PM

thx!

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