hottie99
Forum Guru
Topics: 31
Posts: 604
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ok, so i was told in pass prgam that yes, Berger's disease has IgA deposition, Henoch schonlien purpura has IgA deposition, but i was also told Alports has IgA deposition, now i can't read that anywhere, is this true, or should i scrap this idea??? please let me know!! thanx so much!! 
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| hottie99
Forum Guru
Topics: 31
Posts: 604
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anyone?? thoughts, disputes, agreement????? 
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| taipei817
Forum Junior
Topics: 2
Posts: 78
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i doubt that alport has IgA, i remember reading somewhere that alport does not immunostain or something like that. If IgA were present, i would have been able to be stained.
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| bianca99
Forum Junior
Topics: 2
Posts: 79
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I think alport's is the one where you have defective synthesis of alpha-5 chain of collagen IV.. which btw forms GBM ...
Please correct me if i am wrong people..
Also can anyone tell where do we see defect in alpha-3 subunit of collagen type IV
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| bianca99
Forum Junior
Topics: 2
Posts: 79
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No IgA association though...thats for sure...
And its X linked dominant
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| hottie99
Forum Guru
Topics: 31
Posts: 604
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not sure bianca on the alpha-3 defect, which gn is it??
thx for the clarification on the IgA, much appreicatd peoples!! good luc!
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