bobby
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In case of C1 esterase inhibitor deficiency, which complement components are elevated
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| asmi
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C2 derived kinins ( also complements in alternative pathway like C4 )
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| mdwannabe
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C4 is part of classical path. Alternative path is C3, Fac B, and ussual C5
Classical path, C1, C2, C3 and C4.
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| asmi
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correcto mundo 
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| mdwannabe
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I c u picked up on the lingo :-)
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| mdwannabe
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I c u picked up on the lingo :-)
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"Life not lived for others, is not worth living" Uncle Einstein
"A life is not important, except in the impact it has on other lives" -Jackie Robinson
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| bobby
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so which are the components that will be elevated in a case with C1 esterase inhibitor deficiency?
what are the C2 derived kinins, examples please.
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| mdwannabe
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C2a abd C2b, split by activated C4b that is made by C1 esterase (s-component), both C2 (a, b) are weak kinins, both are part of C3 and C5 convertase, C4a has its own inhibitor, so may not be as high as C2 split by-products.
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"Life not lived for others, is not worth living" Uncle Einstein
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