antidepressant
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1. DIC-Is it more common in female? or is it equally common in both male and female?
2. Ticlopidine inhibit ADP enhanced GP IIb-IIIa expression, thereby inhibit fibrinogen and platelet aggregation. Then how it causes endothelial damage? (table 14-2, RR goljan, page 266, TTP)
3. what happen in platelet count in liver disease? laboratory finding is similar like DIC in following:
a. increased PT and PTT
b. Increased FDP and D-dimer
c. Increased bleeding time. (page 271, RRgoljan)
In DIC, platelet count is decreased. so, if both lab finding is same, we have to differentiate from history, right?
I would appreciate if someone answer number 1 question only. Thanks.
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| 1.ammara
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Ans to q.1
well, as far i know, there is no male or female prepondrence of DIC, but infact,the most common cause of DIC is obstetric complications in females, accounting for more than 50% cases of DIC. this is due to release of thromboplastins from placenta, dead retained foetus or amniotic fluid embolism.
hope this helps!
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| antidepressant
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thank you ammara, it helped.
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