chromosomal translocations

Prep for USMLE Forum

» Log in | Register

Forum

Step 1

Match

Prep4USMLE Forum » USMLE Step 1 Forum » Pathology Forum

chromosomal translocations

Author

10 Posts

astro
Forum Newbie

Topics: 6
Posts: 18

04/10/04 - 12:03 PM

which leukaemias and lymphomas are caused by the following translocations:

a) t(14:18) - bcl2-IgH
b) t(8:14) - cmyc-IgH
c) t(9:22) - bcr-abl
d) t(8:22) - cmyc-kappa light chain
e) t(2:8) - cmyc- lambda light chain

astro
Forum Newbie

Topics: 6
Posts: 18

04/10/04 - 12:05 PM

hmmm... lets try again
a) should be t (14: 18 )
e) is t(2:8 )

asmi
Forum Hero

Topics: 1043
Posts: 4,609

04/10/04 - 12:14 PM

[quote="astro"]which leukaemias and lymphomas are caused by the following translocations:

a) t(14:18) - bcl2-IgH-------->follicular lymphoma/small cleaved cell
b) t(8:14) - cmyc-IgH------>burkitts

c) t(9:22) - bcr-abl--------->CML
d) t(8:22) - cmyc-kappa light chain---------->burkitts
e) t(2:8) - cmyc- lambda light chain-------> burkitts[/quote

asmi
Forum Hero

Topics: 1043
Posts: 4,609

04/10/04 - 12:16 PM

:arrow: t (11; 14 )--->mantle cell /MM /small cell lymphoma
:arrow: t (11 ; 22)---->ewings sarcoma
:arrow: t (15; 17)---->M3 type AML

astro
Forum Newbie

Topics: 6
Posts: 18

04/10/04 - 12:49 PM

correct

bobby
Forum Guru

Topics: 136
Posts: 569

04/11/04 - 08:35 AM

"asmi" wrote:
:arrow: t (11; 14 )--->mantle cell /MM /small cell lymphoma
:arrow: t (11 ; 12)---->ewings sarcoma
:arrow: t (15; 17)---->M3 type AML

ewing's sarcoma is t(11;22)

___________________
if you haven't any charity in your heart, you have the worst kind of heart trouble.

asmi
Forum Hero

Topics: 1043
Posts: 4,609

04/11/04 - 10:00 AM

"bobby" wrote:

"asmi" wrote:
:arrow: t (11; 14 )--->mantle cell /MM /small cell lymphoma
:arrow: t (11 ; 12)---->ewings sarcoma
:arrow: t (15; 17)---->M3 type AML

ewing's sarcoma is t(11;22)

:oops: thanks bobby i didn't realised it ,that was a typing mistake

kalsam
Forum Elite

Topics: 31
Posts: 361

04/16/04 - 03:41 PM

Hi guys..

Does anyone has pneumonic for these stuffs to remember...

Everytime its kind of confusing for me...especially numbers..Thanks

___________________
"Read Repeat Recall Remember Recognise & Reproduce"

mash
Forum Fanatic

Topics: 147
Posts: 1,326

04/17/04 - 08:35 PM

fr more egs, visit
http://www.slh.wisc.edu/cytogenetics/BMproject/BM...

___________________
I hear and I forget. I see and I remember. I do and I understand.
--Confucius

kalsam
Forum Elite

Topics: 31
Posts: 361

04/18/04 - 11:34 AM

#10

Thanks..mash

___________________
"Read Repeat Recall Remember Recognise & Reproduce"

You don't have permission to post.