| Author | 6 Posts |
Justice
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Please vote with your answer
A 17-year-old male adolescent is hospitalized because of a pyogenic liver abscess. He has had numerous episodes of bacterial pneumonia, sinusitis, skin infections, and other infections for most of his life. Results of previous studies for immunoglobulin and neutrophil disorders were normal. A total hemolytic complement (CH50) value was 3 standard deviations below the mean.
Which of the following laboratory studies is most appropriate to attempt to identify the cause of this patients multiple infections?
A. C3
B. Properdin
C. C5
D. IgA
E. C1 inhibitor (C1 INH)
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| aspire
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Guess work by me.
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| CocaCola
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same here
???
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| godfather1212m
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i believe it is C
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WE MIGHT HAVE COME FROM DIFFERENT PLACES, BUT WE ARE HEADING IN THE SAME DIRECTION
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| godfather1212m
Forum Senior
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i believe it is C
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WE MIGHT HAVE COME FROM DIFFERENT PLACES, BUT WE ARE HEADING IN THE SAME DIRECTION
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| Justice
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The correct answer is A
C3 deficiency is one of the most severe complement component deficiencies because it is associated with large numbers of serious pyogenic infections. A total hemolytic complement (CH50) level would be expected to be low in the presence of a low to absent C3 value.
Properdin and C5 deficiencies are associated only with increased numbers of neisserial infections. The patients IgA value was previously normal, so there is no need to repeat this study. Cl inhibitor (Cl INH) deficiency is the cause of hereditary angioedema and is not known to be associated with increased numbers of infections.
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