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TCA energy yield
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Author2 Posts
  #1

Some one some where mentioned that TCA yields 38 molecules of ATP per glucose. I tried to calculate the enery yield myself, but can not achieve more than 32 ATPs per glucose. My calculation is as follows:

Glycolysis:

4 ATP (substrate level phosphorylation) + 2 NADH - 2 ATP

= 2 ATP + 6 ATP = 8 ATP (malate shuttle)

TCA:

2 x (3 NADH + 1 GTP + 1 FADH2)

= 2 x (9 ATP + 1 ATP + 2 ATP) = 24 ATP

TOTAL:

8 + 24 = 32 ATPs

Please correct me if I have made a mistake.


  #2

Everything looks ok... I think you forgrt about pyruvate dehydrogenase. Pyruvate to acetyl-coA is considering to be the first step in TCA. This will give you 2 NADH---->
6 ATP







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