macintosh Forum Elite
Topics: 38 Posts: 178
| | 04/08/08 - 04:48 AM  
 
   
 
|   #1 |
How do differentiate an inhibitor of ETC from an uncoupler of oxidative phosphorylation??
|
| sigh Forum Senior
Topics: 15 Posts: 152
| | 04/08/08 - 06:55 AM  
 
   
 
|   #2 |
What I think... Inhibitors bind to components of ETC Uncouplers increase permeability of membrane block e transport increase e transport decrease proton gradient suppress proton gradient decrease ATP s-s suppress ATP s-s
|
| sigh Forum Senior
Topics: 15 Posts: 152
| | 04/08/08 - 10:12 AM  
 
   
 
|   #3 |
I did try to post the tab on my prev. post...looks confusing...here you go again Inhibitors: bind to components of ETC, block e transport, decrease proton gradient, decrease ATP s-s. Uncouplers: increase membrane permeability, increase e transport, suppress proton gradient, suppress ATP s-s. So, the difference in e transport. Does it make sence?
|
| streakr Forum Newbie
Topics: 0 Posts: 3
| | 05/16/08 - 06:28 PM  
 
   
 
|   #4 |
Uncouplers prevent proton pumping, therefore reduced PMF and reduced ATP synthesis. s
|
|
| |
| | | | |