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Kaplan Qbank USMLE



Author10 Posts
  #1

which of the following is the most likely emergence of hiv variants resistant to antiviral drugs?

hiv reverse transcriptase is error prone
Nef is capable of decreaseing cell surface expression of many protiens

Edited by hottie99 on 03/30/08 - 08:29 PM

  #2

anyone got any ideas???? just would like to see a perspective??? thx!nod

  #3

NO one has a thought on this?? where did bioguy go?? madmad

  #4

please????

  #5

hottie99 wrote:
NO one has a thought on this?? where did bioguy go?? madmad


oops, sorry i don't know the answer. will find out soon.


  #6

its revers transcriptase error.....nef upregulates the CD4 receptors


  #7

yes friend, now i know, i wrote that earlier, hehehee good morning for u!! nod

  #8

Dear hottie, the question asks about emergence of VARIANTS. There is only one way to bring in more variants, which is mutation. Among the answer choices, the right answer is having an error prone reverse transcriptase, as errors cause mutant strains of the virus.


  #9

By the way NEF is "Negative Factor". It functions to destroy CD4 molecules on helper T cells. This helps the virus endocytose the T cell while evading host defenses.


  #10

yes that is what i had thought, thx for giving u input allowing me to confirm my initial thought, good luc!! grin







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