macintosh
Forum Elite
Topics: 38
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19. Examination of the lungs at autopsy shows nodular areas of chronic pneumonitis with necrotizing arteritis and focal collections of epithelioid histiocytes. The most likely diagnosis is
O A) desquamative interstitial pneumonia
O B) Goodpasture's syndrome
O C) histiocytosis X
O D) idiopathic pulmonary fibrosis
O E) pulmonary alveolar proteinosis
O F) sarcoidosis
O G) Wegener's granulomatosis
Please explain your answer.
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| Amlo99
Forum Newbie
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I believe it's Wegener G.:
- Necrotizing granulomatous ( giant cells , macrophages, epitheloid cells) arteritis
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| macintosh
Forum Elite
Topics: 38
Posts: 178
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Agreed. Necrotizing arteritis and focal collections of epithelioid histiocytes are necrotic granulomas in small sized arteries. Histiocytes stand for macrophages. There is lung involvement without mentioning of renal involvement. Wegener primarily affects the lung.
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