bioguy
Forum Guru
Topics: 40
Posts: 747
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dowjunk wrote:
and as u think its over:
Q7 A 35-year-old man with a history of rhinitis and asthma presents to his physician with complaints of
intermittent severe abdominal pain and a chronic maculopapular rash. Peripheral blood smear
demonstrates a marked eosinophilia. Biopsy of a skin lesion demonstrates necrotizing vasculitis
with large numbers of eosinophils. Which of the following diagnoses is most likely?
A. Churg-Strauss syndrome
B. Leukocytoclastic angiitis
C. Mönckeberg's arteriosclerosis
D. Temporal arteritis
E. Wegener's granulomatosis
A) Churg Strauss
dowjunk wrote:
And take this one:
Q6 A 27-year-old man with AIDS develops a reddish, slightly raised rash on his face, neck, and mouth,
consistent in appearance with Kaposi's sarcoma. Microscopically, the proliferating cells in this
malignancy most closely resemble which of the following?
A. Angiosarcoma
B. Carcinosarcoma
C. Lymphoma
D. Malignant fibrous histiocytoma
E. Melanoma
A) Angiosarcoma
dowjunk wrote:
another of my baby:
Q5 The earliest lesion of atherosclerosis is:
(a)Fatty streak. (b)Fibrous plaque. (c)Medial thinning. (d)Platelet aggregation.
a) Fatty Streak
dowjunk wrote:
Lets throw an easy sily one:
Q4 The lipoprotein most often associated with heart disease is:
(a)Very low density lipoprotein. (b)Chylomicrons. (c)Low density lipoproteins. (d)High density lipoproteins
c) LDL
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| bioguy
Forum Guru
Topics: 40
Posts: 747
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If an embolus passes down the aorta from left heart - what are the chances that it will go into the celiac trunk, inferior mesenteric, renal arteries or all the way down into iliacs.
no need of exact statistics, just rational discussion. this is continuation of my question - differences in thrombus v/s embolism of gut circulation. i don't even know if this is pertinent to USMLE. i am just curious.
a thrombus in inf/sup mesenteric artery is due to atherosclerosis i suppose. so if a thrombus of equal stenosing level occurs in two arteries one supplying to splenic flexure and other to say duodenum then -
infarction occurs in splenic flexure due to watershed concept,
will infarction not occur in duodenum ? if so/not why?
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| bioguy
Forum Guru
Topics: 40
Posts: 747
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new_n_lost wrote:
Potentiator of disease in Primary Pulmonary Hypertension and its Rx (drug)
Hint: This is a classic UW question.
Bon Appetit !!!
well here is one topic i haven't read
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| yarab99
Forum Elite
Topics: 15
Posts: 260
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new_n_lost wrote:
Potentiator of disease in Primary Pulmonary Hypertension and its Rx (drug)
Hint: This is a classic UW question.
Bon Appetit !!!
potentiator is Endothilin cuzing vasoconstriction and pulm Hypertension,,,,treatment with inhibitor of endothilin eg, Bosentan
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| bioguy
Forum Guru
Topics: 40
Posts: 747
|
new_n_lost wrote:
Potentiator of disease in Primary Pulmonary Hypertension and its Rx (drug)
Hint: This is a classic UW question.
Bon Appetit !!!
I agree with yarab
Endothelin - causes vasoconstriction and SMC proliferation
Endothelin Receptor Antagonist - Bosentan
Other Rx modalities -
1. Exogenous NO (vasodilation via cGMP)
2. Prostacyclin analogues (vasodilation via cAMP)
3. Phosphodiesterase inhibitors (vasodilation; PDE decreases cGMP)
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| bioguy
Forum Guru
Topics: 40
Posts: 747
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Vasculitis causing acute MI -
in adults ?
in children ?
Edited by bioguy on 03/29/08 - 07:35 PM
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| bioguy
Forum Guru
Topics: 40
Posts: 747
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Presentation of Apolipoprotein B deficiency - ?
Ok, I don't have patience to wait for the answer. I will answer it myself with some thoughts and please let me know if I am wrong, or you can add some more to it.
Presentation - Hemolytic anemia, Ataxia, Acanthocytes, Vit E def
(HAVE some more fat, dear)
Deficiency of B48 and B100 interrupts the formation of Chylomicrons, VLDL and LDL - so Malabsorption (of fat I suppose) leading to Deficiency of Vitamin (why only E, why not all Fat soluble vitamins) - Vit E def. causes Hemolytic anemia, Ataxia and Acanthocytes.
Excerpt from Harrison's
Most clinical manifestations of abetalipoproteinemia result from defects in the absorption and transport of fat-soluble vitamins. Vitamin E and retinyl esters are normally transported from enterocytes to the liver by chylomicrons, and vitamin E is dependent on VLDL for transport out of the liver and into the circulation. As a consequence of the inability of these patients to secrete apoB-containing particles, patients with abetalipoproteinemia are markedly deficient in vitamin E and are also mildly to moderately deficient in vitamin A and vitamin K.
Edited by bioguy on 03/29/08 - 07:54 PM
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| GOGETA
I'm Dr. GOGETA
Topics: 298
Posts: 2,616
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bioguy wrote:
Vasculitis causing acute MI -
in adults ?
in children ?
Chhildren Kawasaki
Adults PAN
___________________
As a general rule, the better it felt when you said it, the more trouble it's going to get you into.
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| bioguy
Forum Guru
Topics: 40
Posts: 747
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GOGETA wrote:
Chhildren Kawasaki
Adults PAN
welcome GOGETA!!!!
Acute MI in a child is a giveway. If one wants to put together a clinical presentation of Kawasaki without the Acute MI (and ECG changes) how would one do it?
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| bioguy
Forum Guru
Topics: 40
Posts: 747
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is the classification of hyperlipoproteinemia important to remember?
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| new_n_lost
Politically InCorrect
Topics: 650
Posts: 6,056
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bioguy wrote:
If an embolus passes down the aorta from left heart - what are the chances that it will go into the celiac trunk, inferior mesenteric, renal arteries or all the way down into iliacs.
no need of exact statistics, just rational discussion. this is continuation of my question - differences in thrombus v/s embolism of gut circulation. i don't even know if this is pertinent to USMLE. i am just curious.
a thrombus in inf/sup mesenteric artery is due to atherosclerosis i suppose. so if a thrombus of equal stenosing level occurs in two arteries one supplying to splenic flexure and other to say duodenum then -
infarction occurs in splenic flexure due to watershed concept,
will infarction not occur in duodenum ? if so/not why?
I think i answered that.
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
Politically InCorrect
Topics: 650
Posts: 6,056
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yarab99 wrote:new_n_lost wrote:
Potentiator of disease in Primary Pulmonary Hypertension and its Rx (drug)
Hint: This is a classic UW question.
Bon Appetit !!!
potentiator is Endothilin cuzing vasoconstriction and pulm Hypertension,,,,treatment with inhibitor of endothilin eg, Bosentan
BINGO !!!!!!
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| bioguy
Forum Guru
Topics: 40
Posts: 747
|
new_n_lost wrote:bioguy wrote:
If an embolus passes down the aorta from left heart - what are the chances that it will go into the celiac trunk, inferior mesenteric, renal arteries or all the way down into iliacs.
no need of exact statistics, just rational discussion. this is continuation of my question - differences in thrombus v/s embolism of gut circulation. i don't even know if this is pertinent to USMLE. i am just curious.
a thrombus in inf/sup mesenteric artery is due to atherosclerosis i suppose. so if a thrombus of equal stenosing level occurs in two arteries one supplying to splenic flexure and other to say duodenum then -
infarction occurs in splenic flexure due to watershed concept,
will infarction not occur in duodenum ? if so/not why?
I think i answered that.
No you didn't. Thats why I rephrased the entire question. I understand the role played by size of embolus and other characteristics of thrombus. i wanted specifics with respect to Gut circulation, if its out there.
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| dowjunk
Forum Senior
Topics: 13
Posts: 250
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bioguy wrote:
If an embolus passes down the aorta from left heart - what are the chances that it will go into the celiac trunk, inferior mesenteric, renal arteries or all the way down into iliacs.
no need of exact statistics, just rational discussion. this is continuation of my question - differences in thrombus v/s embolism of gut circulation. i don't even know if this is pertinent to USMLE. i am just curious.
a thrombus in inf/sup mesenteric artery is due to atherosclerosis i suppose. so if a thrombus of equal stenosing level occurs in two arteries one supplying to splenic flexure and other to say duodenum then -
infarction occurs in splenic flexure due to watershed concept,
will infarction not occur in duodenum ? if so/not why?
Lets make sure that the thromboemboli phenomenon in GI tract will not give time for angiogenesis, and if it is caused by a preexisting atheroma, the infarctions are rare and if do happen, they are very small!
The superior mesenteric artery is prone to be affected by a thrombus due to the angle at the origin and hence its the small bowel, who's unlucky. Duodenum gets thru due to dual supply by the ending anastomosis of celiac.
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Grad of 2007. Work in progress.......
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| dowjunk
Forum Senior
Topics: 13
Posts: 250
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bioguy, with the way you seem like getting through........do learn  hyperlip (types)......man u 'll get a cool score. No flattering!
___________________
Grad of 2007. Work in progress.......
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