crista
Forum Guru
Topics: 121
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mechanism of action
the adverse reactions for li
therapeutic uses
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| bims
Forum Senior
Topics: 26
Posts: 118
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moa;not well known,?related to phoshoinositol cascade
adverse effx;hypothyroidism,
nephrogenic diabetes insipidus due to ADH antagonism(tx with amiloride,indapamide)
teratogenesis
tremors
clin use;bipolar disorder(mood stabilizer)
add more info pls.
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| usmleasr
Forum Guru
Topics: 105
Posts: 970
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how does it cause DI and hypothyroidism?
what is cardiac teratogenicity ass with?
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| bims
Forum Senior
Topics: 26
Posts: 118
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cardiac teratogenicity is ebstein's abnormality.
pls tell how it causes DI and hypot.
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| usmleasr
Forum Guru
Topics: 105
Posts: 970
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it uncouples receptor from their second messanger system....i.e..TSH -binds its receptor ..but adenylate cyclase system is not activated...similarly ADH binds its receptor..but adenylate cyclase is not activated  8)
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| bims
Forum Senior
Topics: 26
Posts: 118
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<:OOO:> thanks 
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| dr.shar
Forum Elite
Topics: 38
Posts: 236
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why we use amiloride to treat lithium induced nephrogenic diabetis insipidus
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| crista
Forum Guru
Topics: 121
Posts: 408
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thank you guys.
very good.
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