new_n_lost wrote:
C- duffy blood group Ag << The Duffy glycoprotein give the absolute protection only to Vivax malaria. The null presence of the glycoprotein in RBCs of the individuals renders them resistent to the Vivax as Vivax requires the precence of the Glycoprotein.
well didnt know this and look to it up
Thanks for the new information...I chose answer B thinking in general about malaria,but i didn't give attention that it was p.vivax
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| new_n_lost
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Well i had deleted my post cos i had searched it up. Didnt want to ruin it for everybody. Had known something like Duffy that existed but nothing else.
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| yarab99
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NNL you r right  the right answer is C-duffy blood group Ag
P.vivax uses the duffy Ag receptor to enter the red blood cell,hence duffy Ag Negitive individiules are immune to P vivax
HbS : hetrozygoutes are immune to P.falciparum,and it is said thats bcuz P.falciprum cant complete its erythrocytic cycle in the RBC bcuz it is cleaned by the spleen for its abnormal shape( theory)
Edited by yarab99 on 03/11/08 - 11:27 PM
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| macintosh
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The absence of duffy antigen from the RBC membrane makes it resistant to P. vivax. However choice B (i.e. presence of HbS) also seems to be a reasonable answer, as all species of malaria invade the RBCs at some stage of their asexual life cycle. Though I am not sure if the presence of HbS can be confirmed on a plain film examination of the blood from the patient.
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| Tiff
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Great question! Would have chosen that distractor HbS.
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| icarus
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Strongly agree that its a great question ... Thank you so much my friends
Kind regards,
IcarusMD
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| Interferon18
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Agree with Tiff would have chosen HbS......the distractor..great job NNL
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| bactitech
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http://en.wikipedia.org/wiki/Duffy_antigen - good explanation here.
If I learned that in my Blood Bank lectures I had forgotten it. Thanks for making me look it up.
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