tia
Forum Guru
Topics: 50
Posts: 1,192
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i spoke to my friends for 2 hours on phone....seems like i cant break this....well its ok...lets see
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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http://www.youtube.com/watch?v=stZqLuKJV6g&featur...
i believe i can i will
passion over comes all the problems ..........and i have never ending passion for my books
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| milee99
Forum Guru
Topics: 54
Posts: 1,282
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hmm tia..
good progress ..
but we must put in more work..
keep hanging there..
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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oh yeah milee i will
thanks for bringing me back to use a timer its keeping a track of where all i can save time
love ya
tia
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| Melu
Forum Senior
Topics: 8
Posts: 248
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Hi Tia,I have been reading your journal from a few days now, it is lively.
I liked the way you are back with a bang!
Keep it up, All the best.
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"The best preparation for good work tomorrow is good work today."- Elbert Hubbard
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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@ melu
hi how are u doing? thank u so much for droppong by
all the best to u too
take care
tia
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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i gotta do 2 block from tommorrow ...........1 block nahhhh not happening
my timer is scaring me ghosh i waste so much time
tiaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa dont do that gaaalllllllll
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| study499
Forum Guru
Topics: 5
Posts: 576
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hey tia,
i like the fact that u r always here...i'm not the only one...
when is ur exam? i use a timer too...but my timer is faster than me ...how do u use ur timer??
sorry for too many qs...my next post will hv no qs...promise
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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pheochromocytomas assc with...neurofibromatosis and MEN 2 and 3
pheo...chromaffin cell..neural crest origin...q stem...head ache...hypertention which is on and off...
adrenal cortex....mesoderm
medulla ....neural crest....
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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hi study499
how are u doing? thanks for dropping by
well i gotta see when will i give my exam...not very sure....
i start 2 timers at a time one of them i stop evrytime i break even if its 2 min...so thats making me realise how much time i am wasting....hope i dont from now...
good luck keep posting
bbye
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| simran2008
Forum Junior
Topics: 1
Posts: 66
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hi tia just droped in to say good luck fr ur prepration me too studying for step one lets encourage each other me doing first aid an uw questions good luck tia
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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hey simran2008
thanks for dropping by
good luck for ur prep too
tc
bbye
tia
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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ahhhhhhh i am bored of FA lemme do a block
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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ok i am done with my block i am too sleepy its too late
ciao
tia
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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hey
good morning
ok i'll start a block in 5 min gotta have coffee
and then get back after review
ciao
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| Mezo
Forum Guru
Topics: 11
Posts: 641
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Hey tia,
how r u ??
FA microbiology is just Soooooooooo Gr888888888 ... Thanks a lot for the advice .. everytime i read bacteriology from kaplan, by the time i reach to the end of it, i forgot all about it, it is well summarized in FA .. i hope other fields are like that too ....
keep it up ...
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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hey mezo
i am fine....good to hear u liked FA....btw have u finished goljan???
ok i finished my block reviewd it too...
will take 15 to 20 min break...
@ milee
hey milee should i read pharma in FA first and then kaplan....i am kinda bad in pharma i feel...do tell me
bbye
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| tia
Forum Guru
Topics: 50
Posts: 1,192
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hey sorryy longer break ...i had food an dwas lazing around
ok will move onto..FA
ciao
tia
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| Mezo
Forum Guru
Topics: 11
Posts: 641
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Hey tia,
Yes, i finished Goljan 4 days ago, done 1 pathophysio test from Q-book, finished Behavioral science yesterday and doing Micro from FA today ... I think Behavioral took that long coz i didn't read it since about 3 months ...
What did u decided about Pharma ??? did u get an answer back from milee ???
How do u plan ur day ?? i c that u sometimes do FA and sometimes Qs ??
keep it up
the last mile
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| Mezo
Forum Guru
Topics: 11
Posts: 641
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Hey tia,
I found this file on my Laptop ... check it out ...
Updates and Corrections to 2007 First Aid for the USMLE Step 1 Revised 4/1/07
Verified Updates, Corrections, and Clarifications
Page HY Fact Comment
p. 70 Written advance directive In addition to directing physicians to withhold or withdraw life-sustaining treatment, a living will can direct physicians as to what life-sustaining treatments a patient wants and does not want.
p. 96 Regulation by F2,6BP The arrows between fructose-6-phosphate and fructose-2,6-bisphosphate should be reversed in direction to be correctly paired with the adjacent enzyme and its function.
p. 98 Electron transport chain and oxidative phosphorylation Uncoupling agents cause a ↓ in the proton gradient, thus causing maximal (↑
consumption of O2 in an unsuccessful attempt to produce ATP. The membrane becomes more permeable to protons.
p. 101 Transport of ammonium by alanine and
glutamine In the transamination reaction depicted in the second diagram, glutamine should be replaced with α-ketoglutarate.
p. 102 Phenylketonuria Phenylalanine hydroxylase catalyzes the reaction of L-phenylalanine to Ltyrosine,
in the process converting THB to DHP. The arrow should be drawn only in this direction.
p. 104 Purine salvage deficiencies
In the figure, the arrows going from IMP to AMP are reversed. IMP to AMP is shown as one step; however, this is actually a two-step process.
p. 105 Glycogen Glycogen synthase is the enzyme that catalyzes the formation of α (1→ 4) glycosidic bonds in glycogen. The number 1 should therefore be adjacent to the arrow just below where it is currently. The enzyme that catalyzes glucose-1- phosphate into UDP glucose is UDP-glucose pyrophosphorylase.
p.111 Porphyrias The enzyme lacking in acute intermittent porphyria is now referred to as porphobilinogen deaminase or hydroxymethylbilane synthase, rather than uroporphyrinogen synthase.
p. 111 Heme synthesis In the figure: δ-aminolevulinic acid does not negatively inhibit ALA synthetase. Instead, heme, the end product of this pathway, represses ALA synthetase activity. ALA synthetase is also known as ALA synthase.
p. 122 Embryologic derivatives
Not all of the cranial nerves are derived from the neural crest; thus “cranial nerves” should be removed from this list.
p. 125 Fetal circulation The single umbilical vein should be shaded to represent “highly oxygenated
blood” and the two umbilical arteries should be unshaded to represent “less oxygenated blood.”
p. 145 Bugs causing diarrhea
1) O157:H7 should be paired with enterohemorrhagic E. coli.
2) Shigella organisms have recently been found to be motile.
p. 163 HIV immunity CXCR1 should be replaced with CXCR4. Mutations in CXCR4 do not clearly affect progression to AIDS.
p. 191 Complement It would be more accurate to state “Deficiency of C1 esterase inhibitor leads to
hereditary angioedema (overactive bradykinin).” It has recently been shown that complement C1 esterase inhibitor inhibits kinin pathways as well as complement, and increased kinin activity is what causes angioedema.
p.204 Paraneoplastic effects of tumors
“Bone metastasis (lysed bone)” should be removed from the list of paraneoplastic causes of hypercalcemia because direct bone lysis is not a ‘paraneoplastic’ phenomenon.
1
P-450p. 223 P-450 interactions Quinidine is a (CYP2D6) P-450 inhibitor and an inducer of a different form (CYP3A4). Isoniazid is generally considered a P-450 inhibitor but has also been shown to activate the isozyme CYP2E1.
p. 224 Herbal agents St. John’s wort is an inducer of the P-450 system, not an inhibitor.
p. 231 Auscultation of the heart
Pulmonic stenosis results in a systolic murmur, not a diastolic murmur as labeled under the pulmonic area on the diagram.
p.241 Congenital heart disease
Children may squat to increase PVR, not venous return.
p.244 Infarcts: red vs. pale
The liver should be listed as an example of red infarcts to be consistent with the figure. The brain should be removed from the list of pale infarcts, as both pale and red infarcts can occur in the brain depending on the location.
p.247 Heart murmurs The aortic regurgitation murmur can also be described as an early diastolic decrescendo murmur.
p. 249 Pericarditis
Findings include ECG changes with diffuse ST-segment elevation, usually with the exception of aVR and V1. There is also notable PR-segment depression.
p.281 Femoral region The femoral artery label should be femoral nerve; the adjacent dark strip should be labeled femoral artery; and the right-most strip should be labeled femoral vein.
p.286 Regulation of gastric acid secretion
On the right side of the figure, all of the drugs listed are depicted as inhibitors of the particular receptor. However, misoprostol is a PG receptor agonist rather than an antagonist.
p. 287 Liver anatomy Zone III is most sensitive to toxic injury, not zone I.
p. 293 Colorectal cancer Peutz-Jeghers syndrome has been associated with an ↑ risk for colorectal cancer
in addition to other malignancies.
p. 293 Colorectal cancer “Apple core” lesions for colorectal cancer are seen on barium enema, not barium
swallow.
p. 296 Reye’s syndrome The third phrase should read: “Associated with viral infection treated with
salicylates.” Reye’s syndrome is not independently associated with salicylate use.
p. 326 Smooth muscle contraction
The right-most part of the diagram should be changed to: “Cross-bridge formation with contraction.” After the action of MLCP, “contraction” should be changed to “relaxation”. The dephosphorylation of the myosin light chain causes muscle relaxation.
p. 363 Primary brain tumors In the supratentorial diagram, the pilocytic astrocytoma labeled “F” is incorrectly placed in the anterior fossa. It is most often found in the posterior fossa, near the region labeled for “B.”
p.337 Immunosuppressive agents: sites of action
In addition to step 4, tacrolimus also acts at steps 2 and 3, in a mechanism similar to that of cyclosporine.
p. 394 Nephron physiology
In diagram E, the intercalated pump is shown as having a Na+/H+ exchanger at the luminal surface. This should be a K+/H+ exchanger.
p. 397 Acidosis/alkalosis At the first branch point, along with pH < 7.4 and pH > 7.4, the terms acidosis
and alkalosis should be replaced with acidemia and alkalemia.
p. 400 Glomerular pathology
SLE may be characterized by subendothelial deposits (as in the figure) and/or subepithelial deposits (as in the text) depending on the pathologic classification.
p. 401 Transitional cell carcinoma
Schistosomiasis should be removed from the fourth line of the entry, and the final S in the mnemonic Pee SACS should be removed to read Pee SAC.
Schistosomiasis is associated with an ↑ incidence of squamous cell carcinoma.
p.431 Obstructive lung disease (COPD)
Up arrow FVC is incorrect. FVC is reduced because the airways close prematurely at high lung volumes, yielding increased RV and therefore lower FVC.
Typographical or Formatting Errors
Page HY Fact Comment
p. 69 Core ethical principles “Benificence” should be changed to “beneficence.”
p. 88 Protein synthesis Beside “Initiation” it should read “40S ribosomal subunit.”
p.96 Glycolytic enzyme deficiency
Glucose phosphate (4%) should read glucose phosphate isomerase (4%).
p. 99 Pentose phosphate pathway (HMP shunt)
The lines “All reactions of this pathway…used or produced.” and “Sites: lactating …steroid synthesis.” are printed in duplicate.
p. 101 Transport of ammonium by alanine
and glutamine In the second diagram, “Apartate” should be replaced with “Aspartate.”
p. 106 Glycogen storage diseases
The enzyme deficient in von Gierke’s disease is glucose-6-phosphatase.
p. 191 Complement The second paragraph should read “Membrane attack complex”
p. 254 Cardiac glycosides Next to Mechanism, “ionotropy” should be replaced with “inotropy.”
p. 263 Adrenal steroids The enzyme that converts pregnenolone to progesterone is 3β- hydroxysteroid dehydrogenase, not 33-hydroxysteroid dehydrogenase.
p. 282 Inguinal canal The line connecting the label “Deep inguinal ring” to the deeper portion of
the canal is missing.
p. 357 Visual field defects In the diagram on the right, there should be a line going across the fibers
adjacent to the number 6.
p.431 Restrictive lung disease VC should be replaced with FVC.
p.432 Obstructive vs. restrictive lung disease
Above the graphs, the FEV1/FVC ratio for restrictive should read > 80%.
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Experience is what u get when u don't get what u want to get
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