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Kaplan Qbank USMLE



Author7 Posts
  #1

Increasing urine flow rate from 1 ml/min to 10 mL/min significantly increase the clearance of

a.-Creatinine

b.-Inulin

c.-Penicillin

d.-Phosphate

e.-Urea


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Great works are performed not by strength, but by perseverance.

  #2

C... lousy derivation: creatine & urea are regulated substance. inulin rep RPF which shouldnt change much as well as the GFR which is rep by creatine clearance

  #3

e.Urea

High flow rate indicates low ADH therefore decreased reabsopbtion of urea and increased clearance




  #4

penicillin

  #5

taipei817 wrote:
C... lousy derivation: creatine & urea are regulated substance. inulin rep RPF which shouldnt change much as well as the GFR which is rep by creatine clearance


inulin represents gfr not rpf

pah represents RPF



  #6

docdoc9 wrote:
e.Urea

High flow rate indicates low ADH therefore decreased reabsopbtion of urea and increased clearance




nodnod

Correct answer E

Urine flow rate is controlled primarily by ADH, which regulates the amount of pure water retained in the urine.

ADH also controls the reabsorption of UREA in the papillary collecting duct. High urine flow rates indicate low ADH, which would increase urea clearance.

In contrast, low urine flow rates indicate high ADH, which would result in a greater reabsorption of urea and a lower urea clearance.


___________________
Great works are performed not by strength, but by perseverance.

  #7

The concentration (and osmolarity) of all other solutes (choices A,B,C, and D) varies inversely with urine flow rate, resulting in no change in clearance. Recall that

Clearance= (urine concentration x urine flow rate) / plasma concentration.


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Great works are performed not by strength, but by perseverance.







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