GoodGirl
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Topics: 93
Posts: 1,215
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A 37-year-old woman develops a malar rash when she spends several hours outside at a cricket match. Ordinarily, she avoids being in the sun, but a friend provided free tickets to a West Indies test match. When she sees her physician, a urinalysis is performed that shows hematuria and proteinuria. A skin biopsy shows immunofluorescence positivity along the dermal-epidermal junction with antibody to C1q. Which of the following additional complications is she most likely to suffer as a consequence of her underlying disease?
A Pulmonary hemorrhage
B Joint ankylosis
C Nodular glomerulosclerosis
D Pulmonary fibrosis
E Pericarditis
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| keepgoing
Forum Guru
Topics: 63
Posts: 1,676
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it SLE,so i go with pericarditis (E)
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| pr20
Forum Senior
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Posts: 168
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E.Pericarditis
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| GoodGirl
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Topics: 93
Posts: 1,215
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Well done ! 
(E) CORRECT. A granular pattern of staining with C1q is characteristic for systemic lupus erythematosus with immune complex deposition with type III hypersensitivity. Immune complexes tend to deposit where basement membranes beneath epithelial and mesothelial surfaces trap them.
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