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Kaplan Qbank USMLE



Author7 Posts
  #1

In a normal patient,if renal vascular resistance is decreased to 50% of its initial value,with no change in renal artery or renal vein pressure,which of the following combinations of changes will occur?

Renal Blood Flow Renal Artery(O2) Renal O2 Use

A) double increase no change

B) double no change increase

C) increase 50% decrease increase

D) increase 50% increase no change

E) decrease 50% no change decrease


  #2

B.??

  #3

B


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  #4

D??


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  #5

Answer is B.

Renal blood flow = (renal artery pressure - renal vein pressure)/renal vascular resistance(RVR).Therefore,if RVR is decreased to halfits original value,with no pressure changes,renal blood flow must double (not increase 50%).Increased blood flow to the kidney and pressure in the glomerular capillaries increase renal oxygen use by increasing GFR,which increases the filtered load of sodium and other solutes.Since active sodium reabsorbtion,which requires more ATP hydrolysis and synthesis( and hence more oxygen use).Renal artery concentration does not change,since it is dependent on normal lung function,not oxygen extraction by the kidney.


  #6

pr20 wrote:
Answer is B.

Renal blood flow = (renal artery pressure - renal vein pressure)/renal vascular resistance(RVR).Therefore,if RVR is decreased to half its original value,with no pressure changes,renal blood flow must double (not increase 50%).Increased blood flow to the kidney and pressure in the glomerular capillaries increase renal oxygen use by increasing GFR,which increases the filtered load of sodium and other solutes.Since active sodium reabsorbtion is load dependent,increased tubular fluid sodium increases all active sodium reasorbtion,which requires more ATP hydrolysis and synthesis( and hence more oxygen use).Renal artery concentration does not change,since it is dependent on normal lung function,not oxygen extraction by the kidney.



  #7

I've missed a line in my first posted answer so i have posted full explanation again..








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