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Kaplan Qbank USMLE



Author6 Posts
  #1

please explain

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  #2

BBBB.. Decreasing myocardial contractility

Beta blocker is very effective and proven to decrease the mortality rate after MI and decrease the incidence of re -infarction in the future

this is because it make the heart to work by a slower rate

- it decrease the heart rate and the cardiac contarctily ,so decrease the cardiac work, deacrease the oxygen supply needed for the myocardium ,decrease the possibility for future MI

- also the beta blocker increase the diastolic filling so ,increasing the Ejection fraction of the heart .increasing the C.O.P so better myocardial blood supply




  #3

B.


  #4

but the answer is C

  #5

Beta blockers don't dilate coronary arteries, but they can constrict peripheral arteries since they block vascular beta 2 receptors which mediate vasodilatation (that is why BB are contraindicated in peripheral vascular disease).

Beta blockers are useful since they block beta 1 receptors, thus decrease HR (don't forget that tachycardia and wall stress are two major factors for oxygen consumption in the heart) = decrease need for O2, also protect from toxic effect of cateholamines


  #6

beta receptor blockers are not strictly contraindicated in peripheral vascular disease. The benefits outweigh the adverse effects in many of these patients, as they usually also have CAD.







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