mdwannabe
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Use of prednisone in Rheum Arth is associated with this adver eff:
1. Hypocalcemia
2. Hyercalcemia
3. Hypothesion
4. Hyper K
5. Hypo K
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| usmleasr
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hypo kalemia :?:
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| dr.shar
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hypocalcemia why
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| merjr
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Hypocalcemia
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| mdwannabe
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I thought it would be Hyper K, cuz of weak menerallo effect that glucks have. But it turned out to be Hypo Ca. But does'nt cortics activate osteoclastes and depress osteoblasts???
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| asmi
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always go for hypocalcemia if choices like above are given...since it most commonly causes osteoporosis
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| mdwannabe
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can u explain better? plz
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"Life not lived for others, is not worth living" Uncle Einstein
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| mdwannabe
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osteo results from over stimul to osteoclast and down reg of blasts.. that increases Ca in plasma.
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"Life not lived for others, is not worth living" Uncle Einstein
"A life is not important, except in the impact it has on other lives" -Jackie Robinson
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| asmi
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it can cause avascular necrosis. and # due to osteoporosis.
http://vasculitis.med.jhu.edu/treatments/predniso...
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| Gul
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but if the calcium is depleted from bone, wont it be increased in blood ?
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| Alina T
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corticosteroids are known to block vitamin D activity --> inhibit intestinal absorbtion of Ca2+ --> hypocalcemia
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