Hepatic Encephalopathy Treatment.

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Hepatic Encephalopathy Treatment.

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DrVirgo
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02/20/08 - 07:54 PM

Hepatic Encephalopathy.

Is neomycin still used as part of the treatment for Hepatic Encephalopathy?
-One UW question (updated 2006) says it is no longer used due to issues with efficacy and toxicity.
-Another UW question (updated 2008) says it IS used.

Any thoughts or ideas on this???

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DrVirgo
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02/22/08 - 08:22 AM

Anyone? Besides Lactulose, any other thoughts on treatment of Hepatic Encephalopathy?

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farnsworth
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02/22/08 - 08:37 AM

Antibiotics (neomycin, metronidazole, rifaximine) are 2nd line treatments, as well as zinc, ornithine aspartate, Na+ benzoate, TIPSS, etc
There are other options under investigation (L-carnitine, NMDA receptor antagonists etc), as well as blood purifying systems (MARS)...
The whole matter is sooo complex, I don't feel comfortable answering you question... Sorry!

mildus
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02/22/08 - 01:05 PM

Low protein diet, neomycin, lactulose, prevention of GI bleeding

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