Summer.Thunder
Forum Elite
Topics: 71
Posts: 180
|
woman taking a drug to delay onset preterm labor, after first dose, tremulousness in her hands, which receptor is involved?
from what i got, the drug is probably magnesium sulfate, the answer that i got is beta2, but from my search online, it is more likely to be NMDA
so anyone knows?
|
| new_n_lost
Politically InCorrect
Topics: 650
Posts: 6,056
|
why do you think its NMDA?? Like which drug would produce teh effects of enhanced NMDA receptor activity.
I normally stay away from NBME questions unless the Form is Specified like i have done form 1 and 3 so i attempt only those questions.
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
|
| Tiff
Forum Guru
Topics: 54
Posts: 562
|
Sounds like it's asking for a tocolytic. Beta agonist like Terbutaline which has more selectivity for beta 2. Calcium channel blocker Nifedipine - most likely used and mostly preferred as a tocolytic. Was that an option?
|
| new_n_lost
Politically InCorrect
Topics: 650
Posts: 6,056
|
They informed that the drug given induced tremors in the hands of the patient and then asked that which of the following receptors where involved.
Beta 2
Muscurinic
Dopa
NDMA
Alpha 1
The answer is Beta though Summer feels it should be NMDA so we are discussing it.
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
|
| Tiff
Forum Guru
Topics: 54
Posts: 562
|
If tremors are involved it should be Beta 2. What is the thought process behind NMDA?
|
| WaqasQureshi
Forum Junior
Topics: 3
Posts: 96
|
its beta 2
|
| Summer.Thunder
Forum Elite
Topics: 71
Posts: 180
|
so is the drug "magnesium sulfate?"
from what i found:
Magnesium sulfate is used to treat pre-eclampsia in laboring women
Magnesium sulfate can also delay labor in the case of premature labor, to delay Preterm birth
so i googled it, and i got this on top of the page,
http://rsx.sagepub.com/cgi/content/abstract/1/1/2...
"Magnesium Sulfate Treatment Decreases N-Methyl-D-Aspartate Receptor Binding in the Rat Brain: An Autoradiographic Study"
that is why i am asking
|
| angel23
Forum Guru
Topics: 34
Posts: 665
|
read the question first....they are asking for mangement of preterm labour plus the drug tht causes tremors.......
it is simply ritonadrine....beta 2 agonist ....with most common S/E tremors
does Magnesium sulfate hav tremors as its side effect....??
so therz no ques on which receptors they act....
|
| new_n_lost
Politically InCorrect
Topics: 650
Posts: 6,056
|
angel23 wrote:
read the question first....they are asking for mangement of preterm labour plus the drug tht causes tremors.......
My thoughts exactly.
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
|
| Summer.Thunder
Forum Elite
Topics: 71
Posts: 180
|
oh, yes, now i got it, Ritodrine, it is a beta agonist, i didn't know that before.
Edited by Summer.Thunder on 02/08/08 - 02:06 AM
|
| new_n_lost
Politically InCorrect
Topics: 650
Posts: 6,056
|
Summer.Thunder wrote:
well, "Magnesium sulfate can also delay labor in the case of premature labor, to delay Preterm birth"
so why is it wrong to use magnesium sulfate?
Dude/dudette does magnesium sulfate cause tremors ??
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
|
| sidiyaa
Forum Newbie
Topics: 0
Posts: 39
|
simply because the skeletal muscles have beta 2 receptors ,their stimulation cause tremor, which is a well known side effect in case of asthmatic patient with beat2 agonist ttt.
|
|
| |
| | | | | | | | | | | | |
