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Cl, and Metabolic Alkalosis
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Author5 Posts
  #1

According to the urinary concentration of chloride, how can you discover the cause (or type) af metabolic alkalosis?

  #2

Anyone to answer?!!

  #3

by looking at concentration, if lo, possibly arf. if hi, have to compare it with other electrolytes. can't say much after that.[/code]

  #4

# Low Urine Chloride <10 meq/L

1. Gastrointestinal causes
1. Vomiting
2. Nasogastric suction
3. Chloride-wasting Diarrhea
4. Villous adenoma of colon
2. Renal Causes
1. Diuretic use (Urine Chloride >10 meq/L)
2. Poorly reabsorbable anion
1. Carbenicillin
2. Penicillin
3. Sulfate
4. Phsophate
3. Post-Hypercapnia
3. Exogenous alkali
1. Sodium Bicarbonate (baking soda)
2. Sodium Citrate
3. Lactate
4. Gluconate
5. Acetate
6. Transfusion
7. Antacid
4. Cystic Fibrosis
5. Achlorhydria
6. Contraction alkalosis

# Causes: Normal or High Urine Chloride >20 meq/L

1. Hypertensive Patient
1. Adrenal Disease
1. Primary Hyperaldosteronism
2. Cushing's Syndrome (Pituitary, Adrenal or ectopic)
3. Liddle Syndrome
2. Exogenous steroids
1. Excess mineralcorticoid intake
2. Excess glucocorticoid intake
3. Excessive licorice intake
4. Carbenoxalone
5. Glycyrrhizic acid
6. Chewing Tobacco
2. Normotensive Patient
1. Bartter Syndrome or Gitelman Syndrome
2. Hypokalemia
3. Excessive alkali administration
4. Milk-Alkali Syndrome
5. Refeeding alkalosis

  #5

excellent

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