Tiff
Forum Guru
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A 30 year old African woman has lost 20 lbs during the past 3 months and complains of fever, chills, and a bad cough. She is found to be suffering from multiple infections, including tuberculosis and severe oral yeast infections. Which of the following viral proteins is important for causing the patient's disease but is not essential for replication?
A. Gag
B. gp120
C. Integrase
D. Nef
E. Protease
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| new_n_lost
Politically InCorrect
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D. Nef
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| silver
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Nef
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| jean robert
Forum Guru
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Protease??
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| Tiff
Forum Guru
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D. (Nef) is the correct answer. The patient's disease manifestations are consistent with the diagnosis of AIDS, a syndrome caused by HIV infection. HIV mutants lacking nef do not cause AIDS, but replicate and have been considered for vaccine development.
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