Prep for USMLEPrep for USMLE Forum
   Forum    Step 1  Step 2 CK Step 2 CS Step 3  Match  IMGs Resources Search






Previous Topic | Next Topic  Iron Waste 




 



Author4 Posts
  #1

What is the major pathway for excess Fe (iron) waste in males and females?

And how is it regulated? :-)

___________________
"Life not lived for others, is not worth living" Uncle Einstein
"A life is not important, except in the impact it has on other lives" -Jackie Robinson

  #2

female-menses
male-gastrointestinal d(ulcer)

  #3

Nope. Menses do not occur in both sexes, and ulcer is pathological. see EXCESS loss, meaning phisiological.

___________________
"Life not lived for others, is not worth living" Uncle Einstein
"A life is not important, except in the impact it has on other lives" -Jackie Robinson

  #4

The physiological waste of Iron goes through normal waste of Enterocytes, where as you remeber most Iron stays after absorbtion and binding to cytoplasmic ferritin.
The regulator of such process is Hepsidin, produced by the liver when its stores of hemosiderin are full, the Hepsidin is released to circulation and affects eneterocytes at bottom of crypts in sm. interstine, it downregulates the transposrters on the luminal surface of enterocyte.

___________________
"Life not lived for others, is not worth living" Uncle Einstein
"A life is not important, except in the impact it has on other lives" -Jackie Robinson







You don't have permission to post.




Login or Register to post messages in this topic





















Contact | Leaders | Disclaimer | Privacy

Copyright @ Prep for USMLE. All rights reserved.