jean robert
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60 y.o. XY has a 5 year history of chest pain when doing moderate physical activity, such as climbing a flight of stairs;the pain would subside upon rest. He sustains a head injury in an automobile accident and dies. The family is contacted and consents to an autopsy. Microscopic examination of a section of heart muscle would most likely reveal which of the following pathologic findings?
a) Coagulative necrosis of the subendocardial muscle
b) Dense scar localized to the distribution of one coronary artery
c) Focal fibrosis and subendocardial myocardial vacuolization
d) Heavy neutrophilic infiltrate adjacent to a large area of coagulative necrosis
e) Transmural coagulative necrosis
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| Tiff
Forum Guru
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Don't believe there would be any necrosis involved here.
Choice C
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| paheli
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C
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| pr20
Forum Senior
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I think its C.
5 year history of chest pain when doing moderate physical activity and subsides with rest---->presentation of stable angina.
Other choices look like the pathological changes that occur with different types of MI.
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| seem.bh
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C
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| arlete
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C
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| new_n_lost
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c) Focal fibrosis and subendocardial myocardial vacuolization
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| jean robert
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Correct Answer: C
Repeated episodes of stable angina pectoris typically cause gradual loss of myocytes,which is seen pathologically as small patches of fibrosis and vacuolization of damaged myocytes, typically in subendocardial locations (which are relatively poorly perfused).
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