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Kaplan Qbank USMLE



Author5 Posts
  #1


An 18-year-old man with sickle cell disease comes

to the emergency department because of shortness

of breath for 6 hours. He has had a low-grade

fever, joint aches, and a rash for 3 days. He was

previously healthy and has had few vaso-occlusive

crises. He takes folic acid regularly and has

required no blood transfusions for 8 years. His

hematocrit has been stable at 32%. His

temperature is 38.1


EC (100.6EF), pulse is3, and platelet count is 450,000/mm3.

120/min, respirations are 36/min, and blood

pressure is 120/86 mm Hg. The lungs are clear to

percussion and auscultation. Cardiac examination

shows normal findings. There is no hepatomegaly

or splenomegaly. He has pain with movement of

the joints, but there is no evidence of arthritis. His

hematocrit is 21%, leukocyte count is

11,500/mm

An x-ray of the chest shows normal findings.

Which of the following is the most appropriate

next step in diagnosis?

(A) Hemoglobin electrophoresis

(B) Measurement of bleeding time

(C) Measurement of reticulocyte count

(D) Serum HIV antibody assay

(E) CT scan of the abdomen



please explain ur answer


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  #2

C


  #3

C. aplastic crisis due to Parvovirus infection


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  #4

Sounds like C to confirm aplastic crisis------->the reticulocyte count would be low------->probably due to parvovirus.


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  #5

the answer in my opinion is c coz the rest dont fit in. But the question is that why do sickel ppl get acute abdomen? ( the reason for arthritis is sickling at low 02 tension and RBCs are responsible for O2 carrying in body) would the same principle apply for acute abdomen?

also most likely this pt has autosplenectomy considering his age.


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