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Kaplan Qbank USMLE



Author6 Posts
  #1

Is iron stored in the Hemosiderin and ferritin stores in Ferrous+2 or the Ferric+3 form.?In haemoglobin it is in the ferrous form?

  #2

Ferritin binds Fe 3+, as well as Hemosiderin, and Heme. Fe2+ is the form absorbed.

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  #3

I think thats backward, because methemoglobinemia (which cant bind O2) is oxidized heme (ferric-->ferrous). The iron in heme is 2+ and the absorbed iron is 3+ or 2+ depending on whether it comes from plants or animals.

  #4

I think Idiopathic i right.Iron is in Fe +2 form in Heme and it is absorbed in +2 form in the plants (becauz they contain more acid in the form of ascorbic acid etc. that makes iron to be in Fe +2 form and is absorbed quickly) and +3 forms in the animals.
But I dont know if ferritin and Haemosiderin stores have +2 or +3 ???

  #5

Ferritin and Haemosiderin stores contain Fe+3.

  #6

Heme iron usually comes from animal sources, and nonheme iron usually comes from nonmeat sources (ex. legumes). I thought that the heme iron should be in the 2+ form though, whereas that bound to a chelator (in the form of ascorbate or citrate) would be in the 3+ form.







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