Misrati
Forum Junior
Topics: 10
Posts: 48
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patient complaining of difficulty breathing ,pain in his cheeks , near his nose ,CT reveals mass lesion involves sinuses , nose and pharynx , biopsy showed nonkeratinized squamous cell carcinoma , which of the following associated with the same oncogenic virus that's likely cause of this patient's cancer :
a-Adult T cell leukemia
b-cutaneous violaceous lesions
c-Genital warts
d-Liver cirrhosis
e-Malignant soft tissue mass of the jaw
PS :  please explain
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| Tiff
Forum Guru
Topics: 54
Posts: 563
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I'm torn between (c) - genital warts and (e) malignant soft tissue mass of the jaw.
HPV causes genital warts and can cause oral squamous cell carcinoma
EBV can cause oral/nasopharyngeal squamous cell carcinoma and Burkitts lymphoma.
Not sure which is more likely. 
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| angel23
Forum Guru
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c
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| GoodGirl
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Topics: 92
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If it would be EBV causing Nasopharyngeal Ca, I would not expect such a aggressive growth, and might see lymph node metastases. histological it could be very possibly. So the answer could be E, as for Burkitt lymphoma, African form.
On the other hand, it could be HPV causing so called '' inverted papillomas'', although these are benign, but very aggressive in growth locally what I recall often reoccur after the resection , affecting paranasall sinuses, as in case above. But are not carcinomas as above.
I'm going for : E
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| Tiff
Forum Guru
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Goodgirl - HPV can cause oral squamous cell carcinoma and not just a benign process.
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| GoodGirl
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I guess, you are right Tiff. I just got totally distracted by involved sinuses, just read recently about the papillomas in nasopharingeal area, so it was retrieved easier from my short term memory !  Let's wait for explanation .
Still going for E
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| Tiff
Forum Guru
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Think I'm going to go with C since HPV can be transmitted sexually and therefore probably more likely to manifest as cancer. 
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| docdoc9
Forum Senior
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I m going with E
Nasopharyngeal carcinomas r usually squamous cell carcinomas or undifferentiated carcinomas and have a strong assosciation with EBV virus
Therefore Burkkit's lumphoma(malignant lesion of jaw)
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| Misrati
Forum Junior
Topics: 10
Posts: 48
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whoever picked E are right ...Nasopharyngeal Ca ..EBV -Burkett's 
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| Tiff
Forum Guru
Topics: 54
Posts: 563
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Misrati - do you have an explanation for this question? Could really use it.
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| Tiff
Forum Guru
Topics: 54
Posts: 563
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Misrati - if so, preferably the explanation explaining wrong answers. Thx
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| Ig F
Forum Elite
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Posts: 431
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B and C both seems to be correct..........
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